Does the presence of obstructive non-infarct-related artery disease increase 30-day mortality in patients presenting with STEMI?
Obstructive non-infarct-related artery disease is common in STEMI patients and is associated with a modest increase in 30-day mortality, raising questions about the optimal timing and appropriateness of non-IRA revascularization.
In a retrospective pooled analysis of 8 clinical trials, obstructive non-IRA disease was common among patients presenting with STEMI, and was associated with a modest statistically significant increase in 30-day mortality. These findings require confirmation in prospectively designed studies, but raise questions about the appropriateness and timing of non-IRA revascularization in patients with STEMI.
Park et al. (Sun,) studied this question.