What does this research mean for the field?

The distinction between fibroadenomas and benign phyllodes tumors in pediatric breast fibroepithelial lesions does not impact clinical outcomes. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to characterize pediatric fibroepithelial lesions (FELs) at both molecular and clinical levels.

March 13, 20260 citations

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Clinicopathological and Molecular Characterization of Pediatric Breast Fibroepithelial Lesions: A Cohort Study.

LZLi Zhang WKWeimao Kong LBLongnv Bao

Key Points

This research aims to characterize pediatric fibroepithelial lesions (FELs) at both molecular and clinical levels.
Conducted a cohort study of pediatric cases with breast fibroepithelial lesions.
Compared clinicopathological features of fibroadenomas and benign phyllodes tumors.
Analyzed the impact of lesion type on clinical outcomes.
No significant difference in clinical outcomes between fibroadenomas and benign phyllodes tumors.
Findings support the idea of a diagnostic continuum for pediatric FELs.
Prognostic significance of the distinction between FA and benign PT is limited.

Abstract

Pediatric FELs likely represent a diagnostic continuum. In this cohort, the distinction between FA and benign PT did not impact clinical outcome, suggesting limited prognostic significance.

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Clinicopathological and Molecular Characterization of Pediatric Breast Fibroepithelial Lesions: A Cohort Study.

Key Points

Abstract

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