Comparison of tooth movement using platelet-rich plasma and conventional method in patients with moderate crowding: A split-mouth study

Key Points

• This research aims to evaluate the effectiveness of platelet-rich plasma (PRP) in accelerating tooth movement compared to conventional methods.
• Conducted a split-mouth study with 50 patients.
• Injected PRP on the experimental side after tooth extraction.
• Measured tooth movement at four time points: T0, T1 (21 days), T2 (42 days), T3 (63 days).
• Utilized digital vernier calipers for accurate measurements.
• Analyzed data using paired t-test.
• Found significant acceleration in tooth movement at 21 days (p < 0.001).
• No significant differences in tooth movement were observed at 42 and 63 days.
• PRP appears to enhance early orthodontic tooth movement, but effects weaken over time.