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This research aims to explore how cadherin affects the differentiation of mesenchymal stem cell (MSC) aggregates into liver organoids.

April 1, 20260 citationsOpen Access

Cadherin-mediated differentiation of MSC-derived liver organoids: sequencing at day 7

This research aims to explore how cadherin affects the differentiation of mesenchymal stem cell (MSC) aggregates into liver organoids.
Used cadherin-functionalized PLGA microspheres for differentiation
Performed RNA sequencing on day 7 of organoid development
Analyzed gene expression profiles of differentiated organoids
Identified key genes involved in liver differentiation
Demonstrated successful formation of liver-like structures
Showed enhanced organoid development compared to control conditions

RNA Sequencing results of MSC aggregates differentiated into liver organoids on day 7 using cadherin-functionalized PLGA microspheres

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秦政(Jun Yang) (Thu,) studied this question.

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