June 3, 2011European Journal of Heart Failure150 citations
View Full PaperClinical and Prognostic Effects of Atrial Fibrillation in Heart Failure Patients with Reduced and Preserved Left Ventricular Ejection Fraction
Structured PICO
Does atrial fibrillation increase the risk of death or HF hospitalization in patients with HF-PEF and HF-REF?
P
Population
Patients with heart failure with reduced (HF-REF) and preserved (HF-PEF) left ventricular ejection fraction
I
Intervention
Atrial fibrillation (exposure)
C
Comparator
Absence of atrial fibrillation
O
Outcome
Composite of death or HF hospitalizationcomposite
Atrial fibrillation is an independent prognostic factor for death or heart failure hospitalization in patients with HFpEF, but not in those with HFrEF.
Abstract
Atrial fibrillation is equally common in patients with HF-PEF and HF-REF. In HF-PEF, but not in HF-REF patients, AF was associated with higher NT-proBNP levels and was independently related to death or HF hospitalization.
Cite This Study
Linssen et al. (Fri,) studied this question.