Why the study?
Does atrial fibrillation increase the risk of death or HF hospitalization in patients with HF-PEF and HF-REF?
Does atrial fibrillation increase the risk of death or HF hospitalization in patients with HF-PEF and HF-REF?
Atrial fibrillation is an independent prognostic factor for death or heart failure hospitalization in patients with HFpEF, but not in those with HFrEF.
AF may refine risk stratification in HFpEF; leaves open whether AF-targeted therapy improves outcomes.
Atrial fibrillation is equally common in patients with HF-PEF and HF-REF. In HF-PEF, but not in HF-REF patients, AF was associated with higher NT-proBNP levels and was independently related to death or HF hospitalization.
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Linssen et al. (2011) studied this question.
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