Does upgrade to CRT-D reduce the combined risk of all-cause mortality, heart failure hospitalization, or absence of reverse remodelling in pacemaker or ICD patients with significant RVP burden and reduced ejection fraction?
Upgrading to CRT-D improves clinical and echocardiographic outcomes in patients with reduced ejection fraction and high right ventricular pacing burden compared to ICD therapy alone.
In pacemaker or ICD patients with significant RVP burden and reduced ejection fraction, upgrade to CRT-D compared with ICD therapy reduced the combined risk of all-cause mortality, heart failure hospitalization, or absence of reverse remodelling.
Merkely et al. (2023) studied this question.
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