What question did this study set out to answer?

This research aims to identify brain MRI biomarkers that can predict frailty in older adults.

April 17, 2026Alzheimer s & Dementia0 citationsOpen Access

Brain magnetic resonance imaging biomarkers for future frailty; sub‐study of FINGER trial

JPJohanna PöyhönenUniversity of Helsinki HRHanna‐Maria RoittoFinnish Institute for Health and Welfare JLJenni LehtisaloUniversity of Eastern Finland

Key Points

This research aims to identify brain MRI biomarkers that can predict frailty in older adults.
Analyzed MRI data from participants in the FINGER trial.
Focused on age-related brain changes.
Evaluated the relationship between MRI findings and frailty outcomes.
Identified specific brain biomarkers associated with increased frailty risk.
Suggested that monitoring these biomarkers can aid in future frailty prevention strategies.

Abstract

The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) is registered at ClinicalTrials.gov (no. NCT01041989).

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