What question did this study set out to answer?

The aim is to synthesize functionalized oxazoles using umpolung reactivity of N-sulfonylhydrazones and imino esters.

April 24, 2026Chemical Communications0 citations

Umpolung Reactivity of N-Sulfonylhydrazones and Imino Esters to Access Functionalized Oxazoles

JMJunaid Mohammad PYPokhriyal Yamini DYDongari Yadagiri

Key Points

The aim is to synthesize functionalized oxazoles using umpolung reactivity of N-sulfonylhydrazones and imino esters.
Synthesis of functionalized oxazoles via N-sulfonylhydrazones and imino esters
Light-induced N–S bond cleavage to produce intermediates
Formation of nucleophilic diazo compounds
Successful synthesis of various functionalized oxazoles
Demonstrated effective umpolung reactivity
Intermediates displayed nucleophilic properties leading to further functionalization

Abstract

We report the synthesis of functionalized oxazoles via an umpolung reactivity of N-sulfonylhydrazones and imino esters. The reaction involves light-induced N–S bond cleavage of N-sulfonylhydrazones to produce nucleophilic diazo intermediates...

问 AI

Bookmark

View Full Paper