Not all Tregs in MDS are created equal

Key Points

• This commentary discusses the role of different regulatory T cells (Tregs) in myelodysplastic syndromes (MDS) and their association with disease progression.
• Analysis of findings from Vazquez et al. regarding Treg populations
• Discussion of the CD95+/CD45RA− Treg subset's implications in MDS
• Comparative evaluation of immunosuppressive profiles in Tregs associated with MDS progression.
• CD95+/CD45RA− Tregs are linked to an immunosuppressive profile in MDS progression.
• Higher frequencies of this Treg subset correlate with advanced disease stages.