January 17, 2011Circulation381 citationsOpen Access
View Full PaperReversal of Severe Heart Failure With a Continuous-Flow Left Ventricular Assist Device and Pharmacological Therapy
Structured PICO
Does a continuous-flow left ventricular assist device combined with pharmacological therapy improve reversal of severe heart failure in patients with end-stage heart failure secondary to nonischemic cardiomyopathy?
P
Population
Patients with end-stage heart failure secondary to nonischemic cardiomyopathy
I
Intervention
Continuous-flow left ventricular assist device (nonpulsatile flow) combined with pharmacological therapy
O
Outcome
Reversal of severe heart failure
A combination of a continuous-flow LVAD and pharmacological therapy can achieve reversal of end-stage heart failure in patients with nonischemic cardiomyopathy.
Abstract
Reversal of end-stage heart failure secondary to nonischemic cardiomyopathy can be achieved in a substantial proportion of patients with nonpulsatile flow through the use of a combination of mechanical and pharmacological therapy.