What question did this study set out to answer?

To assess how lanthanide complexation affects the radiolytic stability of Macropa.

April 30, 2026Dalton Transactions0 citationsOpen Access

Effect of lanthanide (III) complexation on the radiolytic stability of Macropa

AGAlexandre GasparUniversité de Montpellier JHJulie HostierUniversité de Montpellier DGDominique Guillaumont

Key Points

To assess how lanthanide complexation affects the radiolytic stability of Macropa.
Examined the interactions of lanthanide ions with Macropa under radiolytic conditions.
Analyzed stability performance of Macropa as a chelator for radionuclides.
Evaluated potential for use in nuclear medicine therapies and diagnoses.
Lanthanide complexation significantly enhances the radiolytic stability of Macropa.
The improved stability suggests better performance of Macropa as a chelator in nuclear settings.

Abstract

The growing use of radionuclides in nuclear medicine for therapy and diagnosis requires the development of chelators that combine high complexation performance with strong radiolytic stability. Macropa, an ether-crown ligand,...

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