< 0.001). Histological analysis revealed that IBP35 attenuated CPA-induced splenic atrophy and lymphoid depletion. In healthy mice, IBP35 modulated immune responses without inducing excessive inflammation. Collectively, these results indicate that IBP35 modulates both innate and adaptive immune readouts and supports immune function under immunosuppressed conditions.
Lee et al. (Fri,) studied this question.