Female sex was not significantly associated with higher adjusted mortality after out-of-hospital cardiac arrest, though women less often underwent coronary angiography and CABG.
Cohort (n=704)
Are there sex-related differences in post-resuscitation care, mortality, and functional status after out-of-hospital cardiac arrest?
Women experience lower rates of coronary angiography and CABG after out-of-hospital cardiac arrest compared to men, though adjusted mortality appears similar.
Effect estimate: 0.10 (95% CI 0.01-0.78)
p-value: p=0.03
BACKGROUND: Out-of-hospital cardiac arrest is more often reported in men than in women. OBJECTIVES: We aimed to assess sex-related differences in post-resuscitation care; especially with regards to coronary angiography, percutaneous coronary intervention, mortality and functional status after out-of-hospital cardiac arrest. METHODS: We included 704 consecutive adult out-of-hospital cardiac arrest-patients with cardiac aetiology in the Copenhagen area from 2007-2011. Utstein guidelines were used for the pre-hospital data. Vital status and pre-arrest comorbidities were acquired from Danish registries and review of patient charts. Logistic regression was used to assess differences in functional status and use of post-resuscitation care. Cox regression was used to assess differences in 30-day mortality. We used 'smcfcs' and 'mice' imputation to handle missing data. RESULTS: : 0.10, CI: 0.01-0.78, p=0.03). There was no difference in functional status at discharge between men and women ( p=1). CONCLUSION: Female sex was not significantly associated with higher mortality when adjusting for confounders. Women less often underwent coronary angiography and coronary artery bypass grafting, but it is not clear whether this difference can be explained by other factors, or an actual under-treatment in women.
Winther‐Jensen et al. (Wed,) conducted a cohort in Out-of-hospital cardiac arrest (n=704). Female sex vs. Male sex was evaluated on 30-day mortality, functional status, and use of post-resuscitation care (0.10, 95% CI 0.01-0.78, p=0.03). Female sex was not significantly associated with higher adjusted mortality after out-of-hospital cardiac arrest, though women less often underwent coronary angiography and CABG.
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