Women have a worse prognosis and undergo fewer coronary angiographies after out-of-hospital cardiac arrest than men
Key result
Female sex shows no link to higher OHCA mortality despite less angiography and CABG use.
- 0.10
- 95% CI 0.01-0.78
- P=0.03
- n=704
Why the study?
Are there sex-related differences in post-resuscitation care, mortality, and functional status after out-of-hospital cardiac arrest?
Population
704 consecutive adult out-of-hospital cardiac arrest patients with cardiac aetiology in the Copenhagen area…
Comparison
Female sex vs Male sex
Design
Cohort
Follow-up
30 days
Authors
Discussion
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Member takes
Implication
Sex differences in post-OHCA angiography and CABG should not yet change practice; leaves open whether disparities reflect bias or appropriate selection.
Study Design
Type
Cohort (n=704)
Structured PICO
Are there sex-related differences in post-resuscitation care, mortality, and functional status after out-of-hospital cardiac arrest?
P
Population
704 consecutive adult out-of-hospital cardiac arrest patients with cardiac aetiology in the Copenhagen area from 2007-2011
I
Intervention
Female sex
C
Comparator
Male sex
O
Outcome
30-day mortality, functional status at discharge, and use of post-resuscitation care (coronary angiography, percutaneous coronary intervention)hard clinical
Main Result
Effect estimate: 0.10 (95% CI 0.01-0.78)
p-value: p=0.03
Women experience lower rates of coronary angiography and CABG after out-of-hospital cardiac arrest compared to men, though adjusted mortality appears similar.
Limitations
- It is not clear whether the difference in angiography and CABG rates can be explained by other factors or an actual under-treatment in women.
Cite This Study
Winther‐Jensen et al. (2017) conducted a cohort in Out-of-hospital cardiac arrest (n=704). Female sex vs. Male sex was evaluated on 30-day mortality, functional status, and use of post-resuscitation care (0.10, 95% CI 0.01-0.78, p=0.03). Female sex was not significantly associated with higher adjusted mortality after out-of-hospital cardiac arrest, though women less often underwent coronary angiography and CABG.