A dual mode turn-on probe for H 2 O 2 sensing via fluorescence and colorimetry in live cells and serum

Key Points

• The study aims to develop and evaluate a dual mode probe for accurate detection of hydrogen peroxide in live cells and serum.
• Developed a probe that utilizes fluorescence and colorimetry for H2O2 detection.
• Tested the probe in live cells and serum samples to assess performance.
• Evaluated the sensitivity and specificity of the dual-mode approach.
• The probe demonstrated a significant increase in fluorescent signal upon H2O2 exposure, indicating high sensitivity.
• Colorimetric changes correlated with H2O2 concentrations, confirming the probe's effectiveness.
• Successful detection in biological samples suggests potential application in physiological studies.