Why the study?
Does intravenous streptokinase reduce mortality in patients with acute myocardial infarction?
Population
595 patients with acute myocardial infarction
Comparison
Intravenous infusion of 2,500,000 IU of… vs Control group
Design
RCT
Follow-up
6 months
Authors
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Streptokinase shows no mortality benefit in acute MI; challenges assumptions of thrombolytic efficacy and directs research to timing and subgroups.
Does intravenous streptokinase reduce mortality in patients with acute myocardial infarction?
An infusion of streptokinase within 24 hours of the onset of acute myocardial infarction does not significantly affect mortality or the course of the illness up to six months.
Aber et al. (1976) studied this question.
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