The encephalomyocarditis protease responsible for cleaving coat precursor protein is a 20,000 molecular weight protein derived from protein D, a component of the viral RNA polymerase.
The protease required for processing picornaviral coat protein is derived from a component of the viral RNA polymerase.
Partial purification of the encephalomyocarditis protease synthesized in extracts from rabbit reticulocytes shows that the activity responsible for cleaving coat precursor protein cosediments with a previously unmapped virus-coded protein with an apparent molecular weight of 20,000. Tryptic analysis shows that this protein is derived from protein D, a virus-coded component of the encephalomyocarditis RNA polymerase.
Palmenberg et al. (Sat,) conducted a other in Encephalomyocarditis virus. The encephalomyocarditis protease responsible for cleaving coat precursor protein is a 20,000 molecular weight protein derived from protein D, a component of the viral RNA polymerase.