Synapse

← Steven A. Rosenberg

Papers by Steven A. Rosenberg

Page 6 · newest first

  1. Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signalingJournal of Clinical Investigation · 2007
  2. Inability to Mediate Prolonged Reduction of Regulatory T Cells After Transfer of Autologous CD25-depleted PBMC and Interleukin-2 After Lymphodepleting ChemotherapyJournal of Immunotherapy · 2007
  3. Enhanced Antitumor Activity of T Cells Engineered to Express T-Cell Receptors with a Second Disulfide BondCancer Research · 2007
  4. IL-2 and IL-15 Each Mediate De Novo Induction of FOXP3 Expression in Human Tumor Antigen-specific CD8 T CellsJournal of Immunotherapy · 2007
  5. Extrathymic Generation of Tumor-Specific T Cells from Genetically Engineered Human Hematopoietic Stem Cells via Notch SignalingCancer Research · 2007
  6. Cytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 geneBlood · 2007
  7. Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8+ T cellsJournal of Clinical Investigation · 2007
  8. Persistence of Tumor Infiltrating Lymphocytes in Adoptive Immunotherapy Correlates With Telomere LengthJournal of Immunotherapy · 2006
  9. Risk of Bowel Perforation in Patients Receiving Interleukin-2 After Therapy With Anti-CTLA 4 Monoclonal AntibodyJournal of Immunotherapy · 2006
  10. Gene Transfer of Tumor-Reactive TCR Confers Both High Avidity and Tumor Reactivity to Nonreactive Peripheral Blood Mononuclear Cells and Tumor-Infiltrating LymphocytesThe Journal of Immunology · 2006
  11. Adoptive Transfer of Vaccine-Induced Peripheral Blood Mononuclear Cells to Patients with Metastatic Melanoma following LymphodepletionThe Journal of Immunology · 2006
  12. Presentation of Tumor Antigens by Dendritic Cells Genetically Modified With Viral and Nonviral VectorsJournal of Immunotherapy · 2006
  13. A Phase I Study on Adoptive Immunotherapy Using Gene-Modified T Cells for Ovarian CancerClinical Cancer Research · 2006
  14. Intralymphatic Dendritic Cell Vaccination Induces Tumor Antigen–Specific, Skin-Homing T LymphocytesClinical Cancer Research · 2006
  15. Enhanced Antitumor Activity of Murine-Human Hybrid T-Cell Receptor (TCR) in Human Lymphocytes Is Associated with Improved Pairing and TCR/CD3 StabilityCancer Research · 2006
  16. Cancer Regression in Patients After Transfer of Genetically Engineered LymphocytesScience · 2006
  17. CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependentBlood · 2006
  18. Intrapatient Dose Escalation of Anti–CTLA-4 Antibody in Patients With Metastatic MelanomaJournal of Immunotherapy · 2006
  19. Transduction of an HLA-DP4–restricted NY-ESO-1–specific TCR into Primary Human CD4+ LymphocytesJournal of Immunotherapy · 2006
  20. Modulation by IL-2 of CD70 and CD27 Expression on CD8+ T Cells: Importance for the Therapeutic Effectiveness of Cell Transfer ImmunotherapyThe Journal of Immunology · 2006
  21. Enterocolitis in Patients With Cancer After Antibody Blockade of Cytotoxic T-Lymphocyte–Associated Antigen 4Journal of Clinical Oncology · 2006
  22. IL-7 Administration to Humans Leads to Expansion of CD8+ and CD4+ Cells but a Relative Decrease of CD4+ T-Regulatory CellsJournal of Immunotherapy · 2006
  23. Application of the Granzyme B ELISPOT Assay for Monitoring Cancer Vaccine TrialsJournal of Immunotherapy · 2006
  24. Comparison of Common γ-Chain Cytokines, Interleukin-2, Interleukin-7, and Interleukin-15 for the In Vitro Generation of Human Tumor-Reactive T Lymphocytes for Adoptive Cell Transfer TherapyJournal of Immunotherapy · 2006
  25. Evaluation of Prime/Boost Regimens Using Recombinant Poxvirus/Tyrosinase Vaccines for the Treatment of Patients with Metastatic MelanomaClinical Cancer Research · 2006
  26. Measuring Tissue-Based Biomarkers by Immunochromatography Coupled with Reverse-Phase Lysate MicroarrayClinical Cancer Research · 2006
  27. Response to Comment on “Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with Melanoma”The Journal of Immunology · 2006
  28. Selective Elimination of Human Regulatory T Lymphocytes In Vitro With the Recombinant Immunotoxin LMB-2Journal of Immunotherapy · 2006
  29. Skin Reactions in a Subset of Patients With Stage IV Melanoma Treated With Anti–Cytotoxic T-Lymphocyte Antigen 4 Monoclonal Antibody as a Single AgentArchives of Dermatology · 2006
  30. Analysis of the Cellular Mechanism of Antitumor Responses and Autoimmunity in Patients Treated with CTLA-4 BlockadeThe Journal of Immunology · 2005
  31. Primary Human T Lymphocytes Engineered with a Codon-Optimized IL-15 Gene Resist Cytokine Withdrawal-Induced Apoptosis and Persist Long-Term in the Absence of Exogenous CytokineThe Journal of Immunology · 2005
  32. IL-2 administration increases CD4+CD25hi Foxp3+ regulatory T cells in cancer patientsBlood · 2005
  33. Telomere Length of Transferred Lymphocytes Correlates with In Vivo Persistence and Tumor Regression in Melanoma Patients Receiving Cell Transfer TherapyThe Journal of Immunology · 2005
  34. Tumor Progression Can Occur despite the Induction of Very High Levels of Self/Tumor Antigen-Specific CD8+ T Cells in Patients with MelanomaThe Journal of Immunology · 2005
  35. Recognition of Fresh Human Tumor by Human Peripheral Blood Lymphocytes Transduced with a Bicistronic Retroviral Vector Encoding a Murine Anti-p53 TCRThe Journal of Immunology · 2005
  36. Inability of a Fusion Protein of IL-2 and Diphtheria Toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to Eliminate Regulatory T Lymphocytes in Patients With MelanomaJournal of Immunotherapy · 2005
  37. Cytotoxic T-Lymphocyte-Associated Antigen-4 Blockage Can Induce Autoimmune Hypophysitis in Patients With Metastatic Melanoma and Renal CancerJournal of Immunotherapy · 2005
  38. Glucocorticoids Do Not Inhibit Antitumor Activity of Activated CD8+ T CellsJournal of Immunotherapy · 2005
  39. Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 + T cellsThe Journal of Experimental Medicine · 2005
  40. High-Efficiency Transfection of Primary Human and Mouse T Lymphocytes Using RNA ElectroporationMolecular Therapy · 2005
  41. Autoimmunity Correlates With Tumor Regression in Patients With Metastatic Melanoma Treated With Anti–Cytotoxic T-Lymphocyte Antigen-4Journal of Clinical Oncology · 2005
  42. Large-Scale Depletion of CD25+ Regulatory T Cells from Patient Leukapheresis SamplesJournal of Immunotherapy · 2005
  43. Central memory self/tumor-reactive CD8 ⁺ T cells confer superior antitumor immunity compared with effector memory T cellsProceedings of the National Academy of Sciences · 2005
  44. TGF-β1 Attenuates the Acquisition and Expression of Effector Function by Tumor Antigen-Specific Human Memory CD8 T CellsThe Journal of Immunology · 2005
  45. Survival, Persistence, and Progressive Differentiation of Adoptively Transferred Tumor-Reactive T Cells Associated with Tumor RegressionJournal of Immunotherapy · 2005
  46. Transfer of a TCR Gene Derived from a Patient with a Marked Antitumor Response Conveys Highly Active T-Cell Effector FunctionsHuman Gene Therapy · 2005
  47. Primary Human Lymphocytes Transduced with NY-ESO-1 Antigen-Specific TCR Genes Recognize and Kill Diverse Human Tumor Cell LinesThe Journal of Immunology · 2005
  48. Adoptive Cell Transfer Therapy Following Non-Myeloablative but Lymphodepleting Chemotherapy for the Treatment of Patients With Refractory Metastatic MelanomaJournal of Clinical Oncology · 2005
  49. CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory CellsThe Journal of Immunology · 2005
  50. Bcl-2 Overexpression Enhances Tumor-Specific T-Cell SurvivalCancer Research · 2005