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← Fady I. Malik

Papers by Fady I. Malik

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  1. Safety and Tolerability of Omecamtiv Mecarbil During Exercise in Patients With Ischemic Cardiomyopathy and AnginaJACC Heart Failure · 2014
  2. Effect of tirasemtiv, a selective activator of the fast skeletal muscle troponin complex, in patients with peripheral artery diseaseVascular Medicine · 2014
  3. Diaphragm Fiber Strength Is Reduced in Critically Ill Patients and Restored by a Troponin ActivatorAmerican Journal of Respiratory and Critical Care Medicine · 2014
  4. Tirasemtiv amplifies skeletal muscle response to nerve activation in humansMuscle & Nerve · 2014
  5. Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathyBrain · 2013
  6. Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutationsJournal of Medical Genetics · 2013
  7. Fast skeletal muscle troponin activator in the dy2J muscular dystrophy modelMuscle & Nerve · 2013
  8. Fast Skeletal Muscle Troponin Activation Increases Force of Mouse Fast Skeletal Muscle and Ameliorates Weakness Due to Nebulin-DeficiencyPLoS ONE · 2013
  9. Safety, tolerability and pharmacodynamics of a skeletal muscle activator in amyotrophic lateral sclerosisAmyotrophic Lateral Sclerosis · 2012
  10. Radial Artery Loop Perforation with a Transient Arterio-Venous Fistula during Transradial CatheterizationJournal of Clinical & Experimental Cardiology · 2012
  11. Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart FailureScience · 2011
  12. Discovery ofOmecamtiv Mecarbilthe First, Selective, Small Molecule Activator of Cardiac MyosinACS Medicinal Chemistry Letters · 2010
  13. Improvement of Cardiac Function by a Cardiac Myosin Activator in Conscious Dogs With Systolic Heart FailureCirculation Heart Failure · 2010
  14. Tubulin GTP hydrolysis influences the structure, mechanical properties, and kinesin-driven transport of microtubules.Journal of Biological Chemistry · 1994
  15. High-resolution tracking of microtubule motility driven by a single kinesin motor.Proceedings of the National Academy of Sciences · 1994
  16. Directional instability of microtubule transport in the presence of kinesin and dynein, two opposite polarity motor proteins.The Journal of Cell Biology · 1992
  17. Nucleotide specificity of the enzymatic and motile activities of dynein, kinesin, and heavy meromyosin.The Journal of Cell Biology · 1991
  18. Cloning and characterization of RNA polymerase core subunits of Chlamydia trachomatis by using the polymerase chain reactionJournal of Bacteriology · 1990