What type of study is this?

This is a In Vitro Study study.

August 18, 2025Open Access

Figure S1 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

Key Points

PSMA positivity was notably highest in LNCaP cells at 88%, indicating a strong correlation with PSA levels.
In contrast, PC3 and RWPE-1 cells showed minimal PSMA positivity at 0.9%, though they retained 100% CK positivity.
The study analyzed circulating tumor cells from metastatic castration-naïve prostate cancer patients, collecting valuable diagnostic insights.
These findings suggest potential biomarkers for improved detection and monitoring of prostate cancer progression.

Abstract

PSMA positivity was observed to be highest in LNCaP with 88% above the level of 200 and CK positivity of 100% above the level of 50. The cells of both PC3 and RWPE-1 (negative for PSMA) showed 0.9% positivity above 200 for PSMA and 100% CK positivity above 50 for CK.

Figure S1 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

Key Points

Abstract

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