Figure S14 from B7-H3 CAR T Cells Are Effective against Ependymomas but Limited by Tumor Size and Immune Response

Key Points

• B7-H3 car T cells show effectiveness against ependymomas, but their efficacy is limited by tumor size.
• A pivotal comparison reveals that the immune response affects the effectiveness of B7-H3 car T cells.
• The study utilized a cell line to analyze the phenotypic characteristics during repeated stimulation.
• Findings suggest improvements in targeting and understanding immune barriers may enhance treatment outcomes.