What question did this study set out to answer?

The review aims to provide a detailed understanding of antihypertensive drugs, their mechanisms, and latest advancements.

January 17, 2026Open Access

Antihypertensive Drugs: An Advanced Comprehensive Review of Mechanisms, Therapies, and Clinical Innovations

SGSnehal Genbhau Tengle*1, Dr. Amita B. Dongar2, Ms. Ashlesha Gaikwad3

Key Result

Antihypertensive pharmacotherapy is evolving with new agents and strategies that enhance individualized care through precision medicine and digital health technologies.

Key Points

The review aims to provide a detailed understanding of antihypertensive drugs, their mechanisms, and latest advancements.
Comprehensive literature review of antihypertensive pharmacotherapy.
Examination of drug classes and combination strategies.
Exploration of precision medicine and digital health technologies.
Antihypertensive pharmacotherapy is evolving with new agents and combination strategies.
Device-based interventions are becoming more integrated into treatment plans.
Precision medicine and pharmacogenomics are enhancing individualized patient care.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Hypertension is a leading global cause of morbidity and mortality.4–6, contributing to cardiovascular, renal, and cerebrovascular disease. Antihypertensive pharmacotherapy continues to evolve, with new agents, combination strategies, and device-basedinterventions.18–23 Precision medicine, pharmacogenomics.26–28 and digital health technologies.24–25 are reshaping individualized care. Overview of Major Antihypertensive Drug Classes (Section supported by Goodman & Gilman.1, Katzung2, Rang & Dale.3

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