What question did this study set out to answer?

This research aims to evaluate how variations in deep inspiration breath hold (DIBH) levels affect dosimetric outcomes in breast cancer treatment.

April 12, 2026Open Access

Using deformable registration to assess dosimetric impact of variability in deep inspiration breath hold (DIBH) levels for left breast treatment

Key Points

This research aims to evaluate how variations in deep inspiration breath hold (DIBH) levels affect dosimetric outcomes in breast cancer treatment.
Utilized deformable registration for dose estimation
Compared the sensitivity of 3DCRT and VMAT to DIBH variability
Analyzed individual patient breath hold movements
3DCRT showed less sensitivity to breath hold variability compared to VMAT
Significant individual variability in plan robustness was observed
The protocol supports personalized technique selection based on DIBH movements

Abstract

Deformable registration-based dose estimation reveals complex organ motion with significant individual variability in plan robustness. 3DCRT is less sensitive to BH variability than VMAT. Our protocol potentially enables individualized approach to selecting technique and tolerances based on patients' DIBH movements.

Using deformable registration to assess dosimetric impact of variability in deep inspiration breath hold (DIBH) levels for left breast treatment

Key Points

Abstract

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