Ottawa Institute of Systems Biology

Recent papers from Ottawa Institute of Systems Biology

1. Developing scientific communication and technical skills using fluorescence microscopy modules in an undergraduate cell biology courseJournal of Microbiology and Biology Education · 2026
2. Hydrogel-Based Strategies for Metabolic Modulation After Myocardial InfarctionJournal of Functional Biomaterials · 2026
3. Syncytiotrophoblast differentiation defects drive ER stress and reprogram placental PSG1 glycosylation in preeclampsiaMolecular Biomedicine · 2026
4. Artificial intelligence applications in microbiota-gut-brain axis research: Implications for Alzheimer's diseaseJournal of Alzheimer s Disease · 2026
5. Gene body architecture predicts isoform diversity across eukaryotic genomesBMC Genomics · 2026
6. TONSL/TONSOKU binding to histone H3.1 is required for DNA repairScience Advances · 2026
7. Mechanisms, Discovery Strategies, and Emerging Opportunities for AI-Assisted Design of Peptides in Cosmetics and Skin HealthPharmaceuticals · 2026
8. Glycobiology-driven therapeutic targeting of glycan-binding proteins: mechanisms, diseases, and clinical translationSignal Transduction and Targeted Therapy · 2026
9. An oncostatin M receptor and chloride intracellular channel 1 crosstalk drives key oncogenic pathways in glioblastomaSignal Transduction and Targeted Therapy · 2026
10. Kinetics Beyond Pose: A Structure-independent Framework for koff Prediction Across Diverse Protein Families2026
11. Covalent Inhibitors of Monoacylglycerol Lipase Induce Conformational Changes and Proteasomal DegradationJournal of the American Chemical Society · 2026
12. Discovery of 3'UTR structural motifs using protein co-localization networks2026
13. Assessing mitochondrial quality in nontraditional animal modelsCanadian Journal of Zoology · 2026
14. CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2Journal of Chemical Information and Modeling · 2026
15. Integrated bioinformatic and in vivo analysis confirms the cardioprotective role of OPA1BMC Cardiovascular Disorders · 2025
16. Pose ensemble graph neural networks to improve docking performances.2025
17. CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-22025
18. Comparative Analysis of Plasma Extracellular Vesicle Isolation Methods for Purity Assessment and Biomarker DiscoveryProteomes · 2025
19. The colonic mucosal virome in inflammatory bowel disease reveals Crassvirales depletion and disease-specific virome featuresGut Microbes · 2025
20. Structure-based discovery of inhibitors of Mac1 domain of nonstructural protein-3 of SARS-CoV-2 by machine learning-augmented screening of chemical space2025