⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

December 9, 2025BMC Cardiovascular DisordersOpen Access

Integrated bioinformatic and in vivo analysis confirms the cardioprotective role of OPA1

Claire Fong-McMaster Serena M. Pulente Luke S Kennedy Tyler K.T. Smith Stephanie Myers Michel N Kanaan Charbel Y Karam Matthew Cope Martin Lévesque Ella McIlroy Ilka Lorenzen‐Schmidt Craig J. Goergen Morgan D. Fullerton Miroslava Čuperlović‐Culf Erin E. Mulvihill Mary‐Ellen Harper

View Full Paper

Ask AI

Bookmark

Share

Key Points

To confirm the cardioprotective role of OPA1 in cardiac health.
Integrated bioinformatic analysis
In vivo analysis of cardiac function
OPA1 supports optimal cardiac function
Highlighting protective contractile and metabolic signaling pathways

Implication

Research demonstrates cardioprotective effects of OPA1 on cardiac function, suggesting important signaling pathways.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Fong-McMaster et al. (2025) studied this question.

synapsesocial.com/papers/69401efa2d562116f28f9907 https://doi.org/10.1186/s12872-025-05413-0

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1OPA1 mediates cardiac function and metabolism: in silico and in vivo evidence2024
2OPA1 Regulates the Effects of Mitochondrial Dynamics Progress of Research on Different Cells of the Heart against Cardiomyopathyreview · 2025
3Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy2024 · 21 citations
4The role of opa1 in mitochondrial remodeling and profibrotic activation of cardiac fibroblastspreclinical · 2026
5OPA1 affects lipid metabolism and atherosclerosis progression2024