Case report demonstrates the recurrence of ileal gastrointestinal stromal tumors, highlighting surgical and targeted therapy management strategies.
Introduction and importance: Recurrence of gastrointestinal stromal tumors (GISTs) can manifest as local recurrence or distant metastases. Various prognostic factors have been identified as significant predictors of the risk of recurrence. Case report: We report the case of an ileal stromal tumor resected 11 years ago, which recurred locally and was managed surgically at our institution. This study has been reported in line with the SCARE 2025 criteria. Clinical discussion: Surgical resection remains the cornerstone of treatment for localized recurrent GISTs, often complemented by neoadjuvant or adjuvant targeted therapy. Conclusion: Decisions regarding the surgical indications in cases of recurrence should be judiciously deliberated within a multidisciplinary forum.
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Kaitouni et al. (2025) studied this question.
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