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August 6, 2025Graefe s Archive for Clinical and Experimental OphthalmologyOpen Access

Changes in choroidal vessel morphology associated with fluid leakage in central serous chorioretinopathy; a comparison of OCTA and ICGA

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Authors

PKPayam KabiriSKSteffen E. KünzelHumboldt-Universität zu BerlinSAShirin Ashraf-VaghefiHumboldt-Universität zu Berlin

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Implication

Multimodal imaging reveals choroidal morphology links to central serous chorioretinopathy, suggesting OCTA as a non-invasive alternative to ICGA.

Key Points

  • Intervortex venous anastomoses significantly increase the likelihood of central serous chorioretinopathy (P = 0.0004, odds ratio 4.829).
  • OCTA and ICGA showed coinciding results in 95.16% of cases when evaluating pachychoroidal changes.
  • OCTA images had less impairment from subretinal fluid compared to ICGA images, improving diagnostic quality.
  • Longitudinal studies are needed to fully understand the causal relationship between choroidal changes and fluid leakage.

Cite This Study

Kabiri et al. (2025) studied this question.

synapsesocial.com/papers/689522129f4f1c896c429956https://doi.org/10.1007/s00417-025-06918-2
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