August 6, 2025Open Access

One-Pot Synthesis of Thiochromone and It’s Derivatives

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One-pot synthesis allows the creation of thiochromones without intermediate purification steps, improving efficiency.
Yields of thiochromones reached up to 81% by using various 3-(arylthiol)propanoic acids as substrates.
This synthetic method simplifies access to important sulfur-heterocycles with known biological activities.
Thiochromones show potential as precursors in the development of new bioactive agents and could help reduce waste in organic synthesis.

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One-pot synthesis produces thiochromones with good yields in various substrates, suggesting efficiency in generating bioactive compounds.

Simpkins et al. (2025) studied this question.

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