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July 14, 2025International Journal of Molecular Medicine

Emerging threat of environmental microplastics: A comprehensive analysis of hepatic metabolic dysregulation and hepatocellular damage (Review)

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Authors

SYSiqing YueSCSiyu ChenYZYu Zhang

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Overview

Review reveals microplastics harm liver function in humans and animals, suggesting urgent research on health risks.

Key Points

  • Microplastics accumulate in the liver, impacting metabolism and causing cell damage.
  • Evidence shows microplastics disrupt lipid metabolism and induce liver cell death.
  • Particle size and exposure time significantly influence the adverse effects of microplastics on the liver.
  • Further research is necessary to fully understand the mechanisms behind microplastic-induced liver injury.

Cite This Study

Yue et al. (2025) studied this question.

synapsesocial.com/papers/689a02afe6551bb0af8cc149https://doi.org/10.3892/ijmm.2025.5584
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Microplastics and Health: A Review on Environmental Exposure, Toxicokinetics and Biological Effects2026 · 3 citations
  2. 2Metabolomics-Based Insights Into the Toxicological Effects and Mechanisms of Microplastics: A Comprehensive Review.2026
  3. 3Microplastic Toxicity and Intestinal Homeostasis: Insights from Microbiome and Gut Barrier Dysfunction2026
  4. 4Microplastics in focus: a silent disruptor of liver health- a systematic review2025 · 13 citations
  5. 5Micro- and Nanoplastics as Disruptors of Digestive and Hepatopancreatic Homeostasis: Insights into the Plastic-Gut-Liver Axis2026 · 5 citations