Supplemental data reveals altered gene expression patterns in mice exposed to ethanol, indicating potential esophageal cancer susceptibility.
Supplementary Figure S3 shows volcano plots and protein expression of ethanol-induced gene changes in mice. (A-E) The volcano plots depicted the differentially expressed genes in mice exposed to 20% ethanol for 8 weeks (A), 20% ethanol for 16 weeks (B), 20% ethanol for 24 weeks (C), 5% ethanol for 16 weeks (D) and 10% ethanol for 16 weeks (E). (F) The protein expression levels of the top dysregulated genes in mice treated with ethanol.
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Niu et al. (2025) studied this question.
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