Functional analysis reveals significant links between regulatory variants and FOXP4 expression levels in esophageal cancer, suggesting implications for gene studies.
Supplementary Figure S4 shows identification and functional analysis of regulatory variants in alcohol-responsive genes. (A) The flowchart of identifying the regulatory variants of alcohol-responsive genes. (B) A significant correlation was found between different genotypes of rs10223516 and the expression levels of FOXP4 in 497 esophageal mucosal tissue samples from the GTEx database. (C) The construction of the pGL3-promoter and pGL3-basic plasmids for the dual luciferase reporter gene assay experiments.
No takes yet. Share an insight, caveat, or question.
Niu et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: