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July 15, 2025

Supplementary Figure 6 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer

Shayna Thomas-Jardin Shruthy Suresh Ariana Arce Nicole Novaresi Qing Deng Emily Stein Lisa Thomas Cheryl Lewis Chul Ahn Bret M. Evers Esra A. Akbay Maria E. Salvatierra Wei Lü Khaja Khan Luisa M. Solis Soto Ignacio I. Wistuba John D. Minna Kathryn A. O’Donnell

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Key Points

Main finding indicates the role of the integrated stress response in controlling immune checkpoints in lung cancer.
CD155 expression was analyzed in surgically resected primary NSCLC patients, revealing significant insights.
The approach utilized detailed characterization techniques to evaluate CD155 levels in tumor samples from patients.
Understanding CD155's function could advance immune therapies and influence treatment strategies for lung cancer.

Implication

Supplementary figure characterizes CD155 expression in primary NSCLC patients, implying its role in immune response modulation.

Abstract

Supplementary Figure 6 shows the characterization of CD155 expression in surgically resected primary NSCLC patients.

Discussion

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Cite This Study

Thomas-Jardin et al. (2025) studied this question.

synapsesocial.com/papers/689a02bce6551bb0af8cc679 https://doi.org/10.1158/0008-5472.29568077

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 5 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer2025
2Supplementary Figure 1 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer2025
3Supplementary Figure 4 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer2025
4Supplementary Figure 3 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer2025
5Supplementary Figure 2 from The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer2025