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July 19, 2025Nutritional NeuroscienceOpen Access

Epigenetic modulations and nutrient interactions in Alzheimer's disease: unveiling potential therapeutic pathways

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Authors

MZMuhammad-Safuan ZainuddinKGKarshini GhaneshNGNavishaa Ganesan

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Overview

Review synthesizes evidence of nutrients impacting epigenetic mechanisms in Alzheimer's disease, suggesting new therapeutic approaches.

Key Points

  • Epigenetic modulations significantly affect Alzheimer's disease progression and symptomatology.
  • Nutrients may influence epigenetic processes, offering potential benefits in managing amyloid-beta and tau pathology.
  • Review analyzes DNA methylation and histone modifications based on in vitro, in vivo, and clinical studies.
  • Understanding nutrient effects on epigenetics may enable novel intervention strategies for Alzheimer's disease.

Cite This Study

Zainuddin et al. (2025) studied this question.

synapsesocial.com/papers/689a02c9e6551bb0af8cceechttps://doi.org/10.1080/1028415x.2025.2526155
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  1. 1Modulating the Gut‐Microbiota‐Brain Axis in Alzheimer's Disease: Therapeutic Potential of Nutritional and Metabolic Factors2026
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  3. 3Bioactive Compounds as Putative Molecules of Neuroplasticity: An Epigenetic Perspective2026
  4. 4Targeting epigenetic mechanisms in amyloid-β–mediated Alzheimer’s pathophysiology: unveiling therapeutic potential2024 · 1 citations
  5. 5Epigenetic Alterations in Alzheimer’s Disease: Impact on Insulin Signaling and Advanced Drug Delivery Systems2024 · 1 citations