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July 21, 2025

Chemical Composition of the Phenolic Profile and Evaluation of Antimicrobial and Cytotoxic Activities of Moroccan Pomegranate (Punica granatum) Peel Extract

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Authors

FKFahd KandsiKBKaouthar EL BIRGUIMFMohamed El fadili

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Overview

Chemical analysis shows antimicrobial and cytotoxic properties in Punica granatum peel, suggesting potential for new treatments.

Key Points

  • Main finding reveals 30 compounds in pomegranate peel, highlighting phenolic acids and flavonoids as key constituents.
  • Quercetin (23.32%), gallic acid (12.85%), and hesperetin (12.11%) are the dominant compounds identified.
  • The extract shows strong antimicrobial activity against Gram-positive bacteria like Bacillus cereus and Staphylococcus aureus.
  • Cytotoxicity assessment indicates selective inhibition with lower IC50 in splenocytes compared to myeloma P3 cell lines.

Cite This Study

Kandsi et al. (2025) studied this question.

synapsesocial.com/papers/689a0614e6551bb0af8cd4c1https://doi.org/10.21203/rs.3.rs-6983468/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of Biological Activity of Pomegranate Peel Extract as Antioxidant, Antimicrobial and Anticancer2024 · 4 citations
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  3. 3Phytochemical profiling and biological activity assessment of aqueous extract from sweet pomegranate (Punica granatum L.) fruit peels collected in the El Oued region, Algeria2026
  4. 4Bioactive Pigments from Punica granatum L. Peel: Phytochemical Profiling, pharmacological screening and Development of Natural Jelly Candy2026
  5. 5Pomegranate peel: Bioactivities as antimicrobial and cytotoxic agents2024 · 34 citations