Analysis shows that oral gargle cfHPV DNA correlates with tumor volume reduction in oropharyngeal cancer, suggesting potential monitoring methods post-radiotherapy.
Supplemental Figure 4: Oral Gargle HPV DNA Collected at Weekly Intervals from Weeks 1 to 4 and Their Associations with Reduction of Target Tumor Volume (TTV) at Week 4. A) Comparison of the reduction of TTV at week 4 in patients with versus without week 4 oral gargle cfHPV DNA clearance; B) week 1 oral gargle cfHPV DNA clearance; C) week 2 oral gargle cfHPV DNA clearance; and D) week 3 oral gargle cefHPV DNA clearance. Positive (i.e. >0) numbers represent tumor volume reduction while negative (i.e. <0) numbers represent tumor volume increase. Statistical test represents Mann-Whitney Test between the 2 groups overlaid by the bolded line. The median and upper and lower quartiles are represented in the bar graphs.
No takes yet. Share an insight, caveat, or question.
Echevarria et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: