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July 23, 2025

Evaluation of Toxicity of the Methanolic Root Extract of Persicaria hydropiper (L.) Delarbre Used for Fertility Regulation during Early Gestational Period in Female Albino Mice

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Authors

JBJuli BairagiPSPurbajyoti SaikiaFBFreeman Boro

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Overview

Evaluation reveals low toxicity and increased exploratory behavior in female mice treated with methanolic extract of persicaria hydropiper, suggesting potential fertility-regulating uses.

Key Points

  • Core findings indicate low toxicity of the methanolic extract of persicaria hydropiper in female mice.
  • No significant acute or behavioral toxicity was observed, alongside enhanced exploratory behavior in treated groups.
  • Histological analyses showed normal liver and kidney structures with only mild hepatotoxicity noted in ovariectomized females.
  • Research highlights the importance of assessing traditional medicines for safe use and potential fertility regulation.

Cite This Study

Bairagi et al. (2025) studied this question.

synapsesocial.com/papers/689a061be6551bb0af8cda24https://doi.org/10.21203/rs.3.rs-7165220/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Investigating the Bioactive Potential of Persicaria hydropiper: GC-MS Profiling and In vivo Exploration of Antinociceptive and Antidiarrheal Effects2024
  2. 2Phytochemical profiling and GC-MS analysis of methanolic leaf extract of Persicaria hydropiper (L.) H. Gross: An important ethnomedicinal plant2024
  3. 3Evaluation of the Antifertility Activity of <i>Paederia foetida</i> Linn. Root Extracts: Indigenous Knowledge of the Mising Tribe of Assam, North-East, India2026
  4. 4Evaluation of antispermatogenic and antifertility properties of Terminalia chebula (Retz.) in albino mice2024 · 2 citations
  5. 5Modulatory Functions of Craterispermum schweinfurthi on the Hypothalamic-Pituitary-Gonadal Axis of Male Wistar Rats in Phenyl Hydrazine Induced Testicular Toxicity2024 · 2 citations