This review highlights microRNAs' roles in diabetic cardiomyopathy, emphasizing their mechanistic pathways and potential as theranostic tools.
Key Points
MAIN FINDING: MicroRNAs significantly contribute to the pathogenesis of diabetic cardiomyopathy, influencing conditions like heart failure.
KEY EVIDENCE: Specific miRNAs such as miR-9 and miR-208a are linked with key mechanistic pathways, including inflammation and apoptosis.
APPROACH: The review evaluates the complex interactions between miRNAs and DCM-related pathways using recent clinical trials and studies.
SIGNIFICANCE: Understanding miRNAs in DCM may lead to novel diagnostic and therapeutic strategies, enhancing patient management in diabetes-related heart conditions.