Genome assembly reveals 906.92 megabases in Trididemnum clinides, highlighting microbial metagenome interactions and potential therapeutic compounds.
<ns7:p>We present a genome assembly from a specimen of <ns7:italic>Trididemnum clinides</ns7:italic> (photosymbiotic ascidian; Chordata; Ascidiacea; Aplousobranchia; Didemnidae). The <ns7:italic>T. clinides</ns7:italic> genome sequence has a total length of 906.92 megabases. Most of the assembly (97.83%) is scaffolded into 23 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 14.98 kilobases in length. The host ascidian has multiple symbionts, including <ns7:italic>Prochloron</ns7:italic>, a bacterial genus that can also synthesise bioactive natural products of interest for potential therapeutic development. Biosynthesis of active compounds sometimes involves microbial associates.</ns7:p>
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Hirose et al. (2025) studied this question.
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