A Systematic Review and Meta-Analysis of Animal Models on the Possible Link Between Periodontitis and Inflammatory Bowel Diseases

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Inoculation with periodontitis-associated bacteria significantly worsens colitis symptoms in animal models.
A total of 34 animal studies were analyzed, linking oral bacteria with increased disease severity in colitis.
Key findings include significant reductions in body weight and colon length due to oral bacterial exposure.
Insights gained emphasize the need for further exploration into the interaction between periodontal health and inflammatory bowel diseases.

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Systematic review reveals a significant link between periodontitis and colitis in animal models, suggesting bacterial influence.

Akash et al. (2025) studied this question.

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