July 31, 2025

Non-coding RNAs in psoriasis : insights into epidermal dysregulation and inflammation

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Non-coding RNAs play critical roles in psoriasis by influencing inflammatory signaling and keratinocyte behavior.
Upregulation of miR-378a in psoriasis enhances skin inflammation through IL-17A activation of NF-KB signaling.
Loss of miR-149 escalates skin inflammation and immune cell infiltration, highlighting its protective role in psoriasis.
A comprehensive atlas of non-coding RNAs reveals specific signatures associated with psoriasis, suggesting future treatment options.

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Research demonstrates how non-coding RNAs influence keratinocyte dysfunction and inflammation in psoriasis, indicating new therapeutic targets.

Jan Cedric Freisenhausen (2025) studied this question.

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Research demonstrates how non-coding RNAs influence keratinocyte dysfunction and inflammation in psoriasis, indicating new therapeutic targets.