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July 31, 2025Journal of Advances in Biology & Biotechnology

Therapeutic Prospects of Mulberry-Derived DNJ: A Review

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Authors

ATA S TejaswiniKAKaveri AramaniMVM K Veenita

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Overview

This review highlights deoxynojirimycin's role in glucose regulation in type 2 diabetes, suggesting additional health benefits in obesity and lipid metabolism.

Key Points

  • Deoxynojirimycin is a natural compound that inhibits α-glucosidase, effectively regulating blood glucose levels.
  • Research shows DNJ may help manage type 2 diabetes, obesity, and improve lipid metabolism.
  • The extraction and purification processes for DNJ have been optimized to enhance yield and bioavailability.
  • DNJ's diverse effects include antiviral, antimicrobial, and hepatoprotective properties, expanding its therapeutic potential.

Cite This Study

Tejaswini et al. (2025) studied this question.

synapsesocial.com/papers/689a094be6551bb0af8cf268https://doi.org/10.9734/jabb/2025/v28i82706
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Critical Review of 1-Deoxynojirimycin (DNJ) 
in Mulberry in Curing Diabetes Mellitus2025
  2. 2Insights into the Activities and Usefulness of Deoxynojirimycin and Morus alba: A Comprehensive Review2025 · 14 citations
  3. 3Metabolic Modulation of Type 2 Diabetes Mellitus by 1-Deoxynojirimycin: A Multifaceted Approach2026 · 1 citations
  4. 4Alginate-Based Carriers Loaded with Mulberry (Morus alba L.) Leaf Extract: A Promising Strategy for Prolonging 1-Deoxynojirimicyn (DNJ) Systemic Activity for the Nutraceutical Management of Hyperglycemic Conditions2024 · 3 citations
  5. 51-Deoxynojirimycin Attenuates High-Glucose-Induced Oxidative DNA Damage via Activating NRF2/OGG1 Signaling2024 · 11 citations