Quality of Patient‐Reported Outcomes in Multiple Myeloma Randomized Controlled Trial Protocols and Publications According to the SPIRIT‐PRO and CONSORT‐PRO guidelines: A Systematic Review

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Systematic review finds gaps in patient-reported outcomes in multiple myeloma trials, highlighting potential for improved reporting methods.

Patient-reported outcomes are vital in multiple myeloma trials but show significant quality gaps.
Only 69% of analyzed protocols were publicly accessible, indicating limited transparency in research.
Common weaknesses in protocols include low attention to missing data strategies and PRO monitoring plans.
Studies with significant findings tended to report PROs more thoroughly, suggesting potential publication bias.

Shah et al. (2025) studied this question.

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Systematic review finds gaps in patient-reported outcomes in multiple myeloma trials, highlighting potential for improved reporting methods.