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August 1, 2025

Morphological Assessment of the Retina and Optic Nerve Head in Healthy Individuals in Erzurum via Optical Coherence Tomography

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Authors

RYR YaganBUBahadır UtluSKSamet Kapakin

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Overview

Anatomical study reveals age-related alterations in optic nerve head and retinal layers, suggesting early neurodegeneration.

Key Points

  • Age-related thinning in the retinal nerve fiber layer was observed, but not statistically significant in this study.
  • Statistically significant changes in optic nerve head parameters were noted, including increased cup-to-disc ratios with age.
  • Thinning in the ganglion cell complex was significant in individuals over 50 years, indicating potential neurodegenerative changes.
  • The findings underscore the importance of age when interpreting optical coherence tomography parameters in healthy individuals.

Cite This Study

Yagan et al. (2025) studied this question.

synapsesocial.com/papers/689a0c6be6551bb0af8cfd57https://doi.org/10.21203/rs.3.rs-7038058/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Age‐Related Topographical Changes in the Normal Human Optic Nerve Head Measured by Scanning Laser Tomography2001
  2. 2Sex- and Age-Related Differences and Determinants of Ganglion Cell Complex and Retinal Nerve Fiber Layer Thickness: A SS-OCT based study2026
  3. 3The Correlation between Retinal Nerve Fibre Layer Thickness, Optic Nerve Head Parameter, and Related Risk Factor in Glaucoma Patient2024
  4. 4Normative profile of retinal nerve fiber layer thickness using spectral domain optical coherence tomography in healthy Omani adults with emmetropic eyes: a cross-sectional study2026
  5. 5Retinal Nerve Fiber layer (RNFL) Thickness Measurement with Optical Coherence Tomography (OCT) in Normal Children2025