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April 1, 2026Optometry and Vision Science

Age‐Related Topographical Changes in the Normal Human Optic Nerve Head Measured by Scanning Laser Tomography

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Authors

HKHélène KergoatMKMarie‐Jeanne KergoatLJLisette Justino

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Overview

Cross-sectional comparison reveals age-related changes in optic nerve head structure and retinal nerve fiber layer thickness in elderly individuals, indicating clinical implications for ocular health.

Key Points

  • This study aims to investigate how advanced aging affects the optic nerve head structure and RNFL thickness in elderly individuals.
  • Cross-sectional study design comparing two groups: older adults (75-88 years) and younger adults (20-32 years).
  • Utilized scanning laser tomography to measure ONH morphology and RNFL thickness.
  • Quantified ONH disc, cup, and rim areas and calculated the cup-to-disc ratio.
  • Older individuals showed increased cup and disc areas.
  • The cup-to-disc area ratio increased with age.
  • RNFL thickness decreased in the elderly compared to younger subjects.

Cite This Study

Kergoat et al. (2001) studied this question.

synapsesocial.com/papers/69cd7af55652765b073a886ehttps://doi.org/10.1002/j.1538-9235.2001.tb01285.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1THE VARIATION AND COVARIATION OF CUP AND DISC DIAMETERS1976 · 200 citations
  2. 2Chronic Human Glaucoma Causing Selectively Greater Loss of Large Optic Nerve Fibers1988 · 566 citations
  3. 3Scanning laser polarimetry in normal subjects and patients with myopia2000 · 64 citations
  4. 4THE ALTERATION AND ASYMMETRY OF CUP AND DISC DIAMETERS1980 · 48 citations
  5. 5Quantification of Nerve Fiber Layer Thickness in Normal and Glaucomatous Eyes Using Optical Coherence Tomography1995 · 882 citations