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August 1, 2025

Supplementary Figure 3 from Moxidectin Unravels the Role of the Hippo–YAP Pathway in Maintaining Immunity of Glioblastoma Multiforme

Itishree Kaushik Robin Rajan Shreyas Gaikwad Mohamed A. Eltokhy Sanjay Srivastava

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Key Points

MAIN FINDING: Moxidectin does not exhibit any general signs of toxicity in glioblastoma research.
KEY EVIDENCE: The results from supplementary figure 3 support moxidectin's safety profile for further studies.
APPROACH: Analysis focused on the hippo–yap pathway's role in maintaining immunity against glioblastoma multiforme.
SIGNIFICANCE: Understanding this pathway could enhance immunotherapy strategies for glioblastoma multiforme.

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Implication

Supplementary figure illustrates lack of toxicity in moxidectin, suggesting its potential as an immunotherapeutic in glioblastoma multiforme.

Abstract

Supplementary Figure 3: Moxidectin did not show any general signs of toxicity.

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Cite This Study

Kaushik et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d01ba https://doi.org/10.1158/1535-7163.29760422

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 1 from Moxidectin Unravels the Role of the Hippo–YAP Pathway in Maintaining Immunity of Glioblastoma Multiforme2025
2Supplementary Figure 2 from Moxidectin Unravels the Role of the Hippo–YAP Pathway in Maintaining Immunity of Glioblastoma Multiforme2025
3Data from Moxidectin Unravels the Role of the Hippo–YAP Pathway in Maintaining Immunity of Glioblastoma Multiforme2025
4Supplementary Figure 2 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
5Supplementary Figure 6 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025