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October 1, 2025Open Access

Supplementary Figure 2 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis

Huijie Yang Jin Cui Peng Su Xiujie Cui Haojie Guo Penghe Yang Shuqing Zhang Chenmiao Zhang Mingxi Fu Zhongbo Li Yinlu Ding Ting Zhuang Jian Zhu Xiaodong Tan

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Key Points

OXTR depletion significantly slows the progression of hepatocellular carcinoma.
This finding highlights the influence of the hippo/yap axis on cancer development.
HCC cells show altered behavior in the absence of the oxytocin receptor.
This research may open new therapeutic avenues targeting the oxytocin receptor in HCC.

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Implication

Oxytocin receptor depletion slows hepatocellular carcinoma progression, suggesting its role in hepatocarcinogenesis.

Abstract

OXTR depletion slows hepatocellular carcinoma progression in HCC cells

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Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21970 https://doi.org/10.1158/0008-5472.30255577

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 7 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
2Supplementary Figure 5 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
3Supplementary Figure 6 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
4Supplementary Figure 3 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
5Supplementary Figure 1 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025