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October 1, 2025

Supplementary Figure 5 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis

Huijie Yang Jin Cui Peng Su Xiujie Cui Haojie Guo Penghe Yang Shuqing Zhang Chenmiao Zhang Mingxi Fu Zhongbo Li Yinlu Ding Ting Zhuang Jian Zhu Xiaodong Tan

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Key Points

OXTR overexpression promotes hepatocellular carcinoma progression, indicating a crucial role in liver cancer.
Pharmacological activation of OXTR accelerated tumor growth in vivo and in vitro, evidencing its influence on cancer dynamics.
Activation of the hippo/yap axis by OXTR suggests complex signaling pathways significant for tumor development.
Understanding the role of OXTR in hepatocellular carcinoma may lead to novel treatment strategies for patients.

Implication

This research demonstrates OXTR regulates the hippo/yap axis, promoting hepatocellular carcinoma, indicating potential therapeutic targets.

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Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a219bf https://doi.org/10.1158/0008-5472.30255559

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 7 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
2Supplementary Figure 2 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
3Supplementary Figure 1 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
4Supplementary Figure 6 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
5Supplementary Figure 3 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025