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October 1, 2025

Supplementary Figure 3 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis

Huijie Yang Jin Cui Peng Su Xiujie Cui Haojie Guo Penghe Yang Shuqing Zhang Chenmiao Zhang Mingxi Fu Zhongbo Li Yinlu Ding Ting Zhuang Jian Zhu Xiaodong Tan

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Key Points

Atosiban significantly inhibits hepatocellular carcinoma progression, reducing tumor growth by impacting the hippo/yap axis.
The core finding emphasizes the role of the oxytocin receptor in regulating hepatocarcinogenesis through its antagonist, atosiban.
Research utilized an experimental approach to examine the effects of atosiban on the hippo/yap signaling pathway in liver cancer.
These findings highlight the oxytocin receptor's potential as a therapeutic target in hepatocellular carcinoma treatment.

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Implication

This research reveals how OXTR antagonist atosiban inhibits hepatocellular carcinoma progression, suggesting potential therapeutic avenues.

Abstract

The OXTR antagonist atosiban inhibits hepatocellular carcinoma progression

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Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21998 https://doi.org/10.1158/0008-5472.30255568

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 4 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
2Supplementary Figure 5 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
3Supplementary Figure 7 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
4Supplementary Figure 2 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
5Supplementary Figure 6 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025