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October 1, 2025

Supplementary Figure 4 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis

Huijie Yang Jin Cui Peng Su Xiujie Cui Haojie Guo Penghe Yang Shuqing Zhang Chenmiao Zhang Mingxi Fu Zhongbo Li Yinlu Ding Ting Zhuang Jian Zhu Xiaodong Tan

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Key Points

Atosiban significantly inhibits the progression of hepatocellular carcinoma, enhancing outcomes in treatment.
Data collected from both patient-derived explant and organoid models underline the potential therapeutic effects.
Assessment involves organoid models to explore the impact on hepatocellular carcinoma under altered receptor regulation.
Findings may indicate new pathways in cancer treatment, highlighting the significance of the hippo/yap axis.

Implication

Evaluation shows atosiban inhibits hepatocellular carcinoma in organoid models, suggesting a role for the hippo/yap axis.

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Cite This Study

Yang et al. (2025) studied this question.

synapsesocial.com/papers/68de68f183cbc991d0a21aac https://doi.org/10.1158/0008-5472.30255562

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 3 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
2Supplementary Figure 2 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
3Supplementary Figure 7 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
4Supplementary Figure 5 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025
5Supplementary Figure 6 from Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis2025